His son, Jason blamed him for his mutation, as it was usually passed along through the Y (male) chromosome. Wanting to get answers, he tells them to go, he'll be fine, but Rogue says that they won't. Stryker doesn't want the mutant to remember the work they did together – he was an animal then, he's an animal now, Stryker just gave him claws. Then, military police in military vans arrived and approached the exhausted Colonel. Stryker was also willing to kill his superiors if they went against his plans by murdering General Munson when he threatened to close the Weapon X Program.He then accompanies Trask to the public demonstration of the Sentinels outside the White House, expressing surprise at the Sentinels' remote activation at the hands of Magneto.
However, Logan managed crash the helicopter that Zero was in. William Stryker was an anti-mutant religious extremist and a former U.S. soldier connected to Weapon X.
S… During this Stryker unleashed Weapon XI to engage and kill Logan.
After finding Kayla "corpse", and got brutally beaten by Sabretooth, Logan encountered Stryker at the hospital.
As a religious man he believed mutants to be an abomination, and was determined to find a cure, not only for his son but for the "mutant problem" in general. Stryker orders to seal the room, but just then Wolverine jumps and kicks the soldiers around him, shifting to Mystique in the process, uses a soldier as a human shield from the guns and slides through the sealing door at the last second, all in mere seconds. Using another mutant, they were able to free Stryker and lure the X-Men again. The next day, Stryker sent Sabretooth to "kill" Kayla. Stryker and his wife decided to visit her parents, in Phoenix, Arizona, but a car crash left them in the Nevada Desert.
Stryker then gave his son a lobotomy to make him more docile and kept him cryogenically frozen. After Stryker was successful, he attempted to kill Silverfox, but she used her mutant abilities to have him walk until feet bleed, and continue walking afterwards.
Stryker went insane, killing mother and child. Soldiers report to Stryker that more mutants are entering the base, but they can't see how many because of an electrical interference. After the bonding was successful, Stryker processed to create the Weapon XI. Logan puts forth his best effort, but is pinned down.
Stryker says that this already is a war and leaves with Yuriko.In the Control Room, a soldier tells Stryker that there's someone coming down the spillway. So Stryker sent Victor to capture the young mutant. Kayla tried to persuade Victor that Stryker was only using them.
Marcy went into labor and Sgt. At first she forced him to put the gun to his own head but killing him was not her style or in her nature. With special lasers, they manage to open Cerebro, and Stryker steps inside.
As Stryker tells Logan he has a job for him, Logan tells Stryker he already has a job. He wakes up to find William Stryker sitting in front of him and Yuriko Oyama standing by the wall. Stryker suffered a great tragedy when his family was killed when the \"Ultimatum Wave\" struck New York. Stryker confirms, saying that they developed the technology that built his plastic prison.Outside, Stryker takes the cables keeping the helicopter on the ground off, but just then Wolverine shows up, punches him and pops his claws in his arm. Thinking the greatest threat to the world was mutants, Stryker became extremely paranoid and was dedicated to advancing the military to combat with these mutant problems should the need ever arise to, going by means of illegal experimentation on mutations. Nothing, and no one will deter me from it!" Logan asks Stryker what's happening, and Stryker tells him that the spillway is about to get flooded because he was trying to relieve the pressure. He asks him where Scott is.
He attempted to lead a spiritual congregation of survivors at a special tent set up in Central Park, but was unable to successfully conduct his service. Stryker angrily accuses Charles of lying and tells him that back when Jason returned from Xavier's school he resented his parents, blaming them for his condition, so he toyed with their minds, projecting visions and scenarios into their brains. Stryker enters the code and steps inside, seeing his son and Xavier.
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